Identifying Pre-Cancerous States in Seemingly Normal Aging Tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time. The research, published Dec. 31 in Cancer Discovery, demonstrates a practical method for simultaneously measuring specific DNA mutations and gene activity in thousands of individual cells from human tissue. The technique is expected to be useful for studying pre-cancerous cells and may ultimately guide early cancer detection and preventive therapies.

https://news.weill.cornell.edu/news/2026/01/scientists-identify-pre-cancerous-states-in-seemingly-normal-aging-tissues